I don't think the First Lady has been ruled out as a mole entirely; she was hiding something, but she confessed to the Pres. that it was that her famiy was not Cuban (who were legally political refugees at the time her family arrived in the US) but Dominican....or so I understood the story. So that is either true and she's human, or not, and it was a cover story. The Pres. was convinced. If she were a mole you'd think that Sophia would be contacting her, and we haven't seen that. Also, with her husband dead, if he is, she'll be powerless and useless. So my guess is, she's not a mole.
If they have the goods on the VP from a previous assassination attempt why not use those? Puzzling.
Can someone remind me who is next in line after the VP? Someone in the Senate? The Sec. of State? I once knew that whole list!
Either they only need to kill 50 million (or more, after all, the world's population was smaller then, so maybe a % of the total is the way to go) to make room for their people, or they plan to make it even more virulent. I agree it's being presented as already more virulent than it was. I mean yes, it killed fairly quickly FOR A FLU in the 1900's, but it already is being presented as if it kills people before they can even leave the table, much less get to a bed.