Click to see Spoiler:
Santana and Brittney will both be in NY. Mr. Schu is gone. Looks like Sue will somehow make her way to NY (blah). Blaine and Artie will both be in NY. Other possible spoilers - Kurt might be in Russia and someone who was in Season 1 will show up in Season 6. The guess is that it will be Karofsky (the gay football player).