I heard this question when I was watching Inside the Actor's studio. Michael J. Fox (love him!) was on.
The question was:
What sound do you hate the most?
His answer is "when your nose whistle's".
I'm sitting at work, and my nose started to whistle driving me so close to insanity for about 20 minutes . So I thought I'd pose the question to find out what sound you hated the most.