I have read three of the books on the list. I read Moby Dick in school and also read Anna Karenina in school. I later read War and Peace on my own.
I don't abandon a book easily because I'm stubborn. The two offhand that I remember were Jewel by Bret Lott and Midnight's Children by Salman Rushdie. The first was an Oprah selection. I got about halfway in and decided I just did not care what was going to happen to any of the characters. The second had an interesting premise, but I just felt like it wasn't getting to the point. I think I have them both stashed in a closet because I figured someday I would force myself to get through them.