Just read this thread for the first time and have to say - WOW! I agree with so many of the ones mentioned here. I think every book I've read has changed my life in the sense that it adds another viewpoint from which to draw compassion. Richard Brautigan (mentioned way back) never fails to enthrall me - his use of words is groundbreaking. My current life-changer is "50 Facts That Should Change the World". One that I read every year is "The Shell Seekers" by Rosamund Pilcher. I don't know what it is, but it really resonates with my core self.